Product overview:

MAPK7 (ERK5) mouse monoclonal antibody, clone LBI2E2

Field of research:

Gap junction, GnRH signaling pathway, MAPK signaling pathway, Neurotrophin signaling pathway

Summary:

The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is specifically activated by mitogen-activated protein kinase kinase 5 (MAP2K5/MEK5). It is involved in the downstream signaling processes of various receptor molecules including receptor type kinases, and G protein-coupled receptors. In response to extracelluar signals, this kinase translocates to cell nucleus, where it regulates gene expression by phosphorylating, and activating different transcription factors. Four alternatively spliced transcript variants of this gene encoding two distinct isoforms have been reported. [provided by RefSeq]

Alternative names:

BMK1; ERK4; ERK5; PRKM7

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

MAPK7

Isotype:

IgG1

Immunogen:

Full length human recombinant protein of human MAPK7 (NP_002740) produced in HEK293T cell.

Clone:

LBI2E2

Conjugation:

Unconjugated

Gene name:

mitogen-activated protein kinase 7

Symbol:

MAPK7

Pathway:

Gap junction, GnRH signaling pathway, MAPK signaling pathway, Neurotrophin signaling pathway

Function:

Druggable Genome, Protein Kinase

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

0.74 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:2000, IF 1:100, FLOW 1:100

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com