Product overview:

GMDS mouse monoclonal antibody, clone LBI2A1

Field of research:

Amino sugar and nucleotide sugar metabolism, Fructose and mannose metabolism, Metabolic pathways

Summary:

GDP-mannose 4,6-dehydratase (GMD; EC 4.2.1.47) catalyzes the conversion of GDP-mannose to GDP-4-keto-6-deoxymannose, the first step in the synthesis of GDP-fucose from GDP-mannose, using NADP+ as a cofactor. The second and third steps of the pathway are catalyzed by a single enzyme, GDP-keto-6-deoxymannose 3,5-epimerase, 4-reductase, designated FX in humans (MIM 137020). [supplied by OMIM]

Alternative names:

GMD; SDR3E1

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

GMDS

Isotype:

IgG2a

Immunogen:

Full length human recombinant protein of human GMDS (NP_001491) produced in HEK293T cell.

Clone:

LBI2A1

Conjugation:

Unconjugated

Gene name:

GDP-mannose 4,6-dehydratase

Symbol:

GMDS

Pathway:

Amino sugar and nucleotide sugar metabolism, Fructose and mannose metabolism, Metabolic pathways

Function:

Druggable Genome

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

0.64 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:2000

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com