Product overview:

SQSTM1 mouse monoclonal antibody, clone LBI4C8

Field of research:

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Summary:

This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone. [provided by RefSeq]

Alternative names:

A170; OSIL; p60; p62; p62B; PDB3; ZIP3

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

SQSTM1

Isotype:

IgG2a

Immunogen:

Full length human recombinant protein of human SQSTM1 (NP_003891) produced in HEK293T cell.

Clone:

LBI4C8

Conjugation:

Unconjugated

Gene name:

sequestosome 1

Symbol:

SQSTM1

Pathway:

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Function:

Druggable Genome, Transcription Factors

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

0.95 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:1000~2000, IF 1:100, FLOW 1:100

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

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Orders:

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