Product overview:

MYD88 mouse monoclonal antibody, clone LBI2B2

Field of research:

Apoptosis, Toll-like receptor signaling pathway

Summary:

This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. These pathways regulate that activation of numerous proinflammatory genes. The encoded protein consists of an N-terminal death domain and a C-terminal Toll-interleukin1 receptor domain. Patients with defects in this gene have an increased susceptibility to pyogenic bacterial infections. Alternate splicing results in multiple transcript variants. [provided by RefSeq]

Alternative names:

MYD88D

Species reactivity:

Human

Host:

Mouse

Target:

MYD88

Isotype:

IgG2a

Immunogen:

Full length human recombinant protein of human MYD88 (NP_002459) produced in HEK293T cell.

Clone:

LBI2B2

Conjugation:

Unconjugated

Gene name:

MYD88 innate immune signal transduction adaptor

Symbol:

MYD88

Pathway:

Apoptosis, Toll-like receptor signaling pathway

Function:

Druggable Genome

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:2000, IHC 1:150, IF 1:100, FLOW 1:100

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

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