Product overview:

LMAN1 mouse monoclonal antibody, clone LBI2B10

Field of research:

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Summary:

The protein encoded by this gene is a type I integral membrane protein localized in the intermediate region between the endoplasmic reticulum and the Golgi, presumably recycling between the two compartments. The protein is a mannose-specific lectin and is a member of a novel family of plant lectin homologs in the secretory pathway of animal cells. Mutations in the gene are associated with a coagulation defect. Using positional cloning, the gene was identified as the disease gene leading to combined factor V-factor VIII deficiency, a rare, autosomal recessive disorder in which both coagulation factors V and VIII are diminished. [provided by RefSeq]

Alternative names:

ERGIC-53; ERGIC53; F5F8D; FMFD1; gp58; MCFD1; MR60

Species reactivity:

Human, Monkey, Mouse, Rat

Host:

Mouse

Target:

LMAN1

Isotype:

IgG1

Immunogen:

Full length human recombinant protein of human LMAN1 (NP_005561) produced in HEK293T cell.

Clone:

LBI2B10

Conjugation:

Unconjugated

Gene name:

lectin, mannose binding 1

Symbol:

LMAN1

Pathway:

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Function:

Druggable Genome, Transmembrane

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

0.59 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:200~500, IF 1:100

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

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Orders:

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