Product overview:

KEAP1 mouse monoclonal antibody, clone LBI1B4

Field of research:

Ubiquitin mediated proteolysis

Summary:

This gene encodes a protein containing KELCH-1 like domains, as well as a BTB/POZ domain. Kelch-like ECH-associated protein 1 interacts with NF-E2-related factor 2 in a redox-sensitive manner and the dissociation of the proteins in the cytoplasm is followed by transportation of NF-E2-related factor 2 to the nucleus. This interaction results in the expression of the catalytic subunit of gamma-glutamylcysteine synthetase. Two alternatively spliced transcript variants encoding the same isoform have been found for this gene. [provided by RefSeq]

Alternative names:

INrf2; KIAA0132; KLHL19; MGC1114; MGC4407; MGC9454; MGC10630; MGC20887

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

KEAP1

Isotype:

IgG1

Immunogen:

Full length human recombinnt protein of human KEAP1(NP_987096) produced in HEK293T cell.

Clone:

LBI1B4

Conjugation:

Unconjugated

Gene name:

kelch like ECH associated protein 1

Symbol:

KEAP1

Pathway:

Ubiquitin mediated proteolysis

Function:

Transcription Factors

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:500~2000, IHC 1:150, FLOW 1:100

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

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