Product overview:

TTL mouse monoclonal antibody, clone LBI3G5

Field of research:

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Summary:

TTL is a cytosolic enzyme involved in the posttranslational modification of alpha-tubulin (see MIM 602529). Alpha-tubulin within assembled microtubules is detyrosinated over time at the C terminus. After microtubule disassembly, TTL restores the tyrosine residues and consequently participates in a cycle of tubulin detyrosination and tyrosination (Erck et al., 2003 [PubMed 14571137]). [supplied by OMIM]. COMPLETENESS: complete on the 3' end.

Alternative names:

MGC46235

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

TTL

Isotype:

IgG1

Immunogen:

Full length human recombinant protein of human TTL (NP_714923) produced in HEK293T cell.

Clone:

LBI3G5

Conjugation:

Unconjugated

Gene name:

tubulin tyrosine ligase

Symbol:

TTL

Pathway:

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Function:

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Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

0.42 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:500

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

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Orders:

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