Product overview:

SPR mouse monoclonal antibody, clone LBI4F5

Field of research:

Folate biosynthesis, Metabolic pathways

Summary:

This gene encodes an aldo-keto reductase that catalyzes the NADPH-dependent reduction of pteridine derivatives and is important in the biosynthesis of tetrahydrobiopterin (BH4). Mutations in this gene result in DOPA-responsive dystonia due to sepiaterin reductase deficiency. A pseudogene has been identified on chromosome 1. [provided by RefSeq]

Alternative names:

SDR38C1

Species reactivity:

Human, Rat

Host:

Mouse

Target:

SPR

Isotype:

IgG1

Immunogen:

Full length human recombinant protein of human SPR (NP_003115) produced in HEK293T cell.

Clone:

LBI4F5

Conjugation:

Unconjugated

Gene name:

sepiapterin reductase

Symbol:

SPR

Pathway:

Folate biosynthesis, Metabolic pathways

Function:

Druggable Genome

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

0.31 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:500~2000, IHC 1:150, IF 1:100, FLOW 1:100

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com