Product overview:

Anti-PIK3AP1 mouse monoclonal antibody, clone LBI7G9

Field of research:

B cell receptor signaling pathway

Summary:

Involved in the activation of phosphoinositide 3-kinase (PI3K) in B-cells and in natural killer (NK) cells. Couples B-cell antigen receptor (BCR) to PI3K activation by providing a docking site for the PI3K subunit PIK3R1, which contributes to B-cell development. Seems to have a complementary role with CD19 in PI3K activation (By similarity). May be involved in the survival of mature B cells via activation of REL (By similarity).

Alternative names:

BCAP

Species reactivity:

Human, Monkey, Mouse, Rat, Dog

Host:

Mouse

Target:

PIK3AP1

Isotype:

IgG1

Immunogen:

Full length human recombinant protein of human PIK3AP1 (NP_689552) produced in HEK293T cell.

Clone:

LBI7G9

Conjugation:

Unconjugated

Gene name:

phosphoinositide-3-kinase adaptor protein 1

Symbol:

PIK3AP1

Pathway:

B cell receptor signaling pathway

Function:

Druggable Genome

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

0.38 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:500~2000, IF 1:100, FLOW 1:100

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com