Product overview:

CD80 mouse monoclonal antibody, clone LBI2E5

Field of research:

Allograft rejection, Autoimmune thyroid disease, Cell adhesion molecules (CAMs), Graft-versus-host disease, Systemic lupus erythematosus, Toll-like receptor signaling pathway, Type I diabetes mellitus, Viral myocarditis

Summary:

The B-lymphocyte activation antigen B7-1 (formerly referred to as B7) provides regulatory signals for T lymphocytes as a consequence of binding to the CD28 (MIM 186760) and CTLA4 (MIM 123890) ligands of T cells. [supplied by OMIM]

Alternative names:

B7; B7-1; B7.1; BB1; CD28LG; CD28LG1; LAB7

Species reactivity:

Human

Host:

Mouse

Target:

CD80

Isotype:

IgG2a

Immunogen:

Full length human recombinant protein of human CD80 (NP_005182) produced in HEK293T cell.

Clone:

LBI2E5

Conjugation:

Unconjugated

Gene name:

CD80 molecule

Symbol:

CD80

Pathway:

Allograft rejection, Autoimmune thyroid disease, Cell adhesion molecules (CAMs), Graft-versus-host disease, Systemic lupus erythematosus, Toll-like receptor signaling pathway, Type I diabetes mellitus, Viral myocarditis

Function:

Druggable Genome, Transcription Factors, Transmembrane

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:2000, IHC 1:150, IF 1:100

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com