Product overview:

Anti-IVD mouse monoclonal antibody, clone LBI5A11

Field of research:

Metabolic pathways, Valine, leucine and isoleucine degradation

Summary:

Isovaleryl-CoA dehydrogenase (IVD) is a mitochondrial matrix enzyme that catalyzes the third step in leucine catabolism. The genetic deficiency of IVD results in an accumulation of isovaleric acid, which is toxic to the central nervous system and leads to isovaleric acidemia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Alternative names:

ACAD2; IVDH

Species reactivity:

Human, Monkey, Mouse, Rat, Dog

Host:

Mouse

Target:

IVD

Isotype:

IgG1

Immunogen:

Full length human recombinant protein of human IVD (NP_002612) produced in HEK293T cell.

Clone:

LBI5A11

Conjugation:

Unconjugated

Gene name:

isovaleryl-CoA dehydrogenase

Symbol:

IVD

Pathway:

Metabolic pathways, Valine, leucine and isoleucine degradation

Function:

Druggable Genome

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

0.66 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:500~2000, IF 1:100, FLOW 1:100

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com