Product overview:

Anti-QPRT mouse monoclonal antibody, clone LBI3B3

Field of research:

Metabolic pathways, Nicotinate and nicotinamide metabolism

Summary:

This gene encodes a key enzyme in catabolism of quinolinate, an intermediate in the tryptophan-nicotinamide adenine dinucleotide pathway. Quinolinate acts as a most potent endogenous exitotoxin to neurons. Elevation of quinolinate levels in the brain has been linked to the pathogenesis of neurodegenerative disorders such as epilepsy, Alzheimer's disease, and Huntington's disease. [provided by RefSeq]. COMPLETENESS: complete on the 3' end.

Alternative names:

HEL-S-90n; QPRTase

Species reactivity:

Human

Host:

Mouse

Target:

QPRT

Isotype:

IgG2a

Immunogen:

Full length human recombinant protein of human QPRT (NP_055113) produced in HEK293T cell.

Clone:

LBI3B3

Conjugation:

Unconjugated

Gene name:

quinolinate phosphoribosyltransferase

Symbol:

QPRT

Pathway:

Metabolic pathways, Nicotinate and nicotinamide metabolism

Function:

Request info at info@sobekbio.com

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

0.75 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:2000, IF 1:50, FLOW 1:100

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com