Product overview:

NUMB mouse monoclonal antibody, clone LBI2C4

Field of research:

Notch signaling pathway

Summary:

The protein encoded by this gene plays a role in the determination of cell fates during development. The encoded protein, whose degradation is induced in a proteasome-dependent manner by MDM2, is a membrane-bound protein that has been shown to associate with EPS15, LNX1, and NOTCH1. Four transcript variants encoding different isoforms have been found for this gene.

Alternative names:

C14orf41; c14_5527; S171

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

NUMB

Isotype:

IgG1

Immunogen:

Full length human recombinant protein of human NUMB (NP_003735) produced in HEK293T cell.

Clone:

LBI2C4

Conjugation:

Unconjugated

Gene name:

NUMB endocytic adaptor protein

Symbol:

NUMB

Pathway:

Notch signaling pathway

Function:

Request info at info@sobekbio.com

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:500, FLOW 1:100

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com