Product overview:

Anti-PAICS mouse monoclonal antibody, clone LBI5B6

Field of research:

Metabolic pathways, Purine metabolism

Summary:

This gene encodes a bifunctional enzyme containing phosphoribosylaminoimidazole carboxylase activity in its N-terminal region and phosphoribosylaminoimidazole succinocarboxamide synthetase in its C-terminal region. It catalyzes steps 6 and 7 of purine biosynthesis. The gene is closely linked and divergently transcribed with a locus that encodes an enzyme in the same pathway, and transcription of the two genes is coordinately regulated. The human genome contains several pseudogenes of this gene. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Alternative names:

ADE2; ADE2H1; AIRC; PAIS

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

PAICS

Isotype:

IgG2b

Immunogen:

Full length human recombinant protein of human PAICS (NP_006443) produced in HEK293T cell.

Clone:

LBI5B6

Conjugation:

Unconjugated

Gene name:

phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase

Symbol:

PAICS

Pathway:

Metabolic pathways, Purine metabolism

Function:

Druggable Genome

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:2000, IF 1:100, Flow: 1:100

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com