Product overview:

Anti-CRYM (mu Crystallin) mouse monoclonal antibody, clone LBI1B5

Field of research:

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Summary:

Crystallins are separated into two classes: taxon-specific and ubiquitous. The former class is also called phylogenetically-restricted crystallins. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. This gene encodes a taxon-specific crystallin protein that binds NADPH and has sequence similarity to bacterial ornithine cyclodeaminases. The encoded protein does not perform a structural role in lens tissue, and instead it binds thyroid hormone for possible regulatory or developmental roles. Mutations in this gene have been associated with autosomal dominant non-syndromic deafness. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq]

Alternative names:

DFNA40; THBP

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

CRYM

Isotype:

IgG2a

Immunogen:

Full length human recombinant protein of human CRYM (NP_001879) produced in HEK293T cell.

Clone:

LBI1B5

Conjugation:

Unconjugated

Gene name:

crystallin mu

Symbol:

CRYM

Pathway:

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Function:

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Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

0.58 mg/ml

Form:

PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB: 1:200 - 1:1000, IHC 1:300, IF 1:100

Storage buffer:

PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

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Orders:

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