Product overview:

Anti-DHPS mouse monoclonal antibody, clone LBI2C9

Field of research:

Request info at info@sobekbio.com

Summary:

The unusual amino acid hypusine is formed posttranslationally and is only found in a single cellular protein, eukaryotic translation initiation factor 5A. In the first step of hypusine biosynthesis, deoxyhypusine synthase catalyzes the NAD-dependent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the EIF5A precursor protein to form the intermediate deoxyhypusine residue. This gene consists of nine exons spanning 6.6 kb. Three transcript variants have been isolated. However, only transcript variant 1 encodes an active protein. The shorter variants may act as modulating factors of DHPS activity. [provided by RefSeq]

Alternative names:

DHS; DS; MIG13

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

DHPS

Isotype:

IgG2a

Immunogen:

Full length human recombinant protein of human DHPS (NP_001921) produced in HEK293T cell.

Clone:

LBI2C9

Conjugation:

Unconjugated

Gene name:

deoxyhypusine synthase

Symbol:

DHPS

Pathway:

Request info at info@sobekbio.com

Function:

Request info at info@sobekbio.com

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

0.85 mg/ml

Form:

PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:2000

Storage buffer:

PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com