Product overview:

Anti-CYB5R3 mouse monoclonal antibody, clone LBI1E3

Field of research:

Amino sugar and nucleotide sugar metabolism

Summary:

This gene encodes cytochrome b5 reductase, which includes a membrane-bound form in somatic cells (anchored in the endoplasmic reticulum, mitochondrial and other membranes) and a soluble form in erythrocytes. The membrane-bound form exists mainly on the cytoplasmic side of the endoplasmic reticulum and functions in desaturation and elongation of fatty acids, in cholesterol biosynthesis, and in drug metabolism. The erythrocyte form is located in a soluble fraction of circulating erythrocytes and is involved in methemoglobin reduction. The membrane-bound form has both membrane-binding and catalytic domains, while the soluble form has only the catalytic domain. Alternate splicing results in multiple transcript variants. Mutations in this gene cause methemoglobinemias. [provided by RefSeq]

Alternative names:

B5R; DIA1

Species reactivity:

Human

Host:

Mouse

Target:

CYB5R3

Isotype:

IgG1

Immunogen:

Full length human recombinant protein of human CYB5R3 (NP_000389) produced in HEK293T cell.

Clone:

LBI1E3

Conjugation:

Unconjugated

Gene name:

cytochrome b5 reductase 3

Symbol:

CYB5R3

Pathway:

Amino sugar and nucleotide sugar metabolism

Function:

Druggable Genome

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

0.7 mg/ml

Form:

PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:500, IF 1:100

Storage buffer:

PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com