Product overview:

Anti-TBXAS1 (Thromboxane synthase) mouse monoclonal antibody, clone LBI1C3

Field of research:

Arachidonic acid metabolism, Metabolic pathways

Summary:

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. However, this protein is considered a member of the cytochrome P450 superfamily on the basis of sequence similarity rather than functional similarity. This endoplasmic reticulum membrane protein catalyzes the conversion of prostglandin H2 to thromboxane A2, a potent vasoconstrictor and inducer of platelet aggregation. The enzyme plays a role in several pathophysiological processes including hemostasis, cardiovascular disease, and stroke. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Alternative names:

BDPLT14; CYP5; CYP5A1; GHOSAL; THAS; TS; TXAS; TXS

Species reactivity:

Human

Host:

Mouse

Target:

TBXAS1

Isotype:

IgG2a

Immunogen:

Full length human recombinant protein of human TBXAS1 (NP_001052) produced in HEK293T cell.

Clone:

LBI1C3

Conjugation:

Unconjugated

Gene name:

thromboxane A synthase 1

Symbol:

TBXAS1

Pathway:

Arachidonic acid metabolism, Metabolic pathways

Function:

Druggable Genome, P450

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

0.63 mg/ml

Form:

PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:500, IHC 1:50, IF 1:100, FLOW 1:100

Storage buffer:

PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com