Product overview:

Anti-GNMT mouse monoclonal antibody, clone LBI8A3

Field of research:

Glycine, serine and threonine metabolism

Summary:

The protein encoded by this gene is an enzyme that catalyzes the conversion of S-adenosyl-L-methionine (along with glycine) to S-adenosyl-L-homocysteine and sarcosine. The encoded protein is found in the cytoplasm and acts as a homotetramer. Defects in this gene are a cause of GNMT deficiency (hypermethioninemia).

Alternative names:

glycine N-methyltransferase; OTTHUMP00000016412

Species reactivity:

Human, Mouse

Host:

Mouse

Target:

GNMT

Isotype:

IgG3

Immunogen:

Full length human recombinant protein of human GNMT (NP_061833) produced in HEK293T cell.

Clone:

LBI8A3

Conjugation:

Unconjugated

Gene name:

glycine N-methyltransferase

Symbol:

GNMT

Pathway:

Glycine, serine and threonine metabolism

Function:

Druggable Genome

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB: 1:200 - 1:1000, Flow 1:100

Storage buffer:

PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com