Product overview:

HSPB8 (Hsp22) mouse monoclonal antibody, clone LBI1E3

Field of research:

Request info at info@sobekbio.com

Summary:

The protein encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The expression of this gene in induced by estrogen in estrogen receptor-positive breast cancer cells, and this protein also functions as a chaperone in association with Bag3, a stimulator of macroautophagy. Thus, this gene appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease. [provided by RefSeq]

Alternative names:

CMT2L; DHMN2; E2IG1; H11; HMN2; HMN2A; HSP22

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

HSPB8

Isotype:

IgG2a

Immunogen:

Full length human recombinant protein of human HSPB8(NP_055180) produced in HEK293T cell.

Clone:

LBI1E3

Conjugation:

Unconjugated

Gene name:

heat shock protein family B (small) member 8

Symbol:

HSPB8

Pathway:

Request info at info@sobekbio.com

Function:

Druggable Genome, Protein Kinase

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

0.88 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:500~2000, IF 1:100, FLOW 1:100

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com