Product overview:

Anti-BAT1 (UAP56) mouse monoclonal antibody, clone LBI2C5

Field of research:

Spliceosome

Summary:

This gene encodes a member of the DEAD box family of RNA-dependent ATPases that mediate ATP hydrolysis during pre-mRNA splicing. The encoded protein is an essential splicing factor required for association of U2 small nuclear ribonucleoprotein with pre-mRNA, and also plays an important role in mRNA export from the nucleus to the cytoplasm. A cluster of genes, BAT1-BAT5, is localized in the vicinity of the genes for TNF alpha and TNF beta. These genes are all within the human major histocompatibility complex class III region. Mutations in this gene may be associated with rheumatoid arthritis. Alternatively spliced transcript variants encoding the same protein have been described.

Alternative names:

BAT1; D6S81E; UAP56

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

DDX39B

Isotype:

IgG2b

Immunogen:

Full length human recombinant protein of human BAT1(NP_542165) produced in HEK293T cell.

Clone:

LBI2C5

Conjugation:

Unconjugated

Gene name:

DExD-box helicase 39B

Symbol:

DDX39B

Pathway:

Spliceosome

Function:

Request info at info@sobekbio.com

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

0.59 mg/ml

Form:

PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:500, IHC 1:50

Storage buffer:

PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com