Product overview:

Anti-NIT1 mouse monoclonal antibody, clone LBI3A11

Field of research:

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Summary:

Play a role in cell growth and apoptosis: loss of expression promotes cell growth and resistance to DNA damage stress. Has tumor suppressor properties that enhances the apoptotic responsiveness in cancer cells; this effect is additive to the tumor suppressor activity of FHIT. it is also a negative regulator of primary T-cells. Has apparently no omega-amidase activity such as NIT2.

Alternative names:

MGC57670

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

NIT1

Isotype:

IgG1

Immunogen:

Full length human recombinant protein of human NIT1 (NP_005591) produced in HEK293T cell.

Clone:

LBI3A11

Conjugation:

Unconjugated

Gene name:

nitrilase 1

Symbol:

NIT1

Pathway:

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Function:

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Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

0.87 mg/ml

Form:

PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:2000, IHC 1:50, IF 1:100, Flow 1:100

Storage buffer:

PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

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Orders:

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