Product overview:

Anti-PTPRE (PTP epsilon) mouse monoclonal antibody, clone LBI5F2

Field of research:

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Summary:

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. Two alternatively spliced transcript variants of this gene have been reported,one of which encodes a receptor-type PTP that possesses a short extracellular domain, a single transmembrane region,and two tandem intracytoplasmic catalytic domains; Another one encodes a PTP that contains a distinct hydrophilic N-terminus, and thus represents a nonreceptor-type isoform of this PTP. Studies of the similar gene in mice suggested the regulatory roles of this PTP in RAS related signal transduction pathways, cytokines induced SATA signaling, as well as the activation of voltage-gated K+ channels.

Alternative names:

HPTPE; PTPE; R-PTP-EPSILON

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

PTPRE

Isotype:

IgG1

Immunogen:

Full length human recombinant protein of human PTPRE (NP_006495) produced in HEK293T cell.

Clone:

LBI5F2

Conjugation:

Unconjugated

Gene name:

protein tyrosine phosphatase receptor type E

Symbol:

PTPRE

Pathway:

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Function:

Druggable Genome, Phosphatase, Transmembrane

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

0.58 mg/ml

Form:

PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:1000, IHC 1:50, IF 1:100

Storage buffer:

PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

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