Product overview:

Anti-ANXA1 (Annexin A1) mouse monoclonal antibody, clone LBI3A8

Field of research:

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Summary:

Annexin I belongs to a family of Ca(2+)-dependent phospholipid binding proteins which have a molecular weight of approximately 35,000 to 40,000 and are preferentially located on the cytosolic face of the plasma membrane. Annexin I protein has an apparent relative molecular mass of 40 kDa, with phospholipase A2 inhibitory activity. Since phospholipase A2 is required for the biosynthesis of the potent mediators of inflammation, prostaglandins and leukotrienes, annexin I may have potential anti-inflammatory activity.

Alternative names:

ANX1; LPC1

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

ANXA1

Isotype:

IgG1

Immunogen:

Full length human recombinant protein of human ANXA1 (NP_000691) produced in HEK293T cell.

Clone:

LBI3A8

Conjugation:

Unconjugated

Gene name:

annexin A1

Symbol:

ANXA1

Pathway:

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Function:

Druggable Genome

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

0.9 mg/ml

Form:

PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:2000, IHC 1:50, IF 1:100

Storage buffer:

PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

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Orders:

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