Product overview:

Anti-RALBP1 (RIP1) mouse monoclonal antibody, clone LBI2A6

Field of research:

Pancreatic cancer, Pathways in cancer

Summary:

Can activate specifically hydrolysis of GTP bound to RAC1 and CDC42, but not RALA. Mediates ATP-dependent transport of S-(2,4-dinitrophenyl)-glutathione (DNP-SG) and doxorubicin (DOX) and is the major ATP-dependent transporter of glutathione conjugates of electrophiles (GS-E) and DOX in erythrocytes. Can catalyze transport of glutathione conjugates and xenobiotics, and may contribute to the multidrug resistance phenomenon. Serves as a scaffold protein that brings together proteins forming an endocytotic complex during interphase and also with CDC2 to switch off endocytosis, One of its substrates would be EPN1/Epsin

Alternative names:

RIP1; RLIP1; RLIP76

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

RALBP1

Isotype:

IgG1

Immunogen:

Full length human recombinant protein of human RALBP1 (NP_006779) produced in HEK293T cell.

Clone:

LBI2A6

Conjugation:

Unconjugated

Gene name:

ralA binding protein 1

Symbol:

RALBP1

Pathway:

Pancreatic cancer, Pathways in cancer

Function:

Request info at info@sobekbio.com

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

0.56 mg/ml

Form:

PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:2000, IHC 1:50, IF 1:100, IP: 4ug/mL

Storage buffer:

PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com