Product overview:

XRCC1 mouse monoclonal antibody, clone LBI2G8

Field of research:

Base excision repair

Summary:

The protein encoded by this gene is involved in the efficient repair of DNA single-strand breaks formed by exposure to ionizing radiation and alkylating agents. This protein interacts with DNA ligase III, polymerase beta and poly (ADP-ribose) polymerase to participate in the base excision repair pathway. It may play a role in DNA processing during meiogenesis and recombination in germ cells. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. [provided by RefSeq]

Alternative names:

RCC

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

XRCC1

Isotype:

IgG1

Immunogen:

Full length human recombinant protein of human XRCC1 (NP_006288) produced in HEK293T cell.

Clone:

LBI2G8

Conjugation:

Unconjugated

Gene name:

X-ray repair cross complementing 1

Symbol:

XRCC1

Pathway:

Base excision repair

Function:

Druggable Genome

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

0.55 mg/ml

Form:

PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:2000, FLOW 1:100

Storage buffer:

PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com