Product overview:

PKMYT1 mouse monoclonal antibody, clone LBI1C3

Field of research:

Cell cycle, Oocyte meiosis, Progesterone-mediated oocyte maturation

Summary:

The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase preferentially phosphorylates and inactivates cell division cycle 2 protein (CDC2), and thus negatively regulates cell cycle G2/M transition. This kinase is associated with the membrane throughout the cell cycle. Its activity is highly regulated during the cell cycle. Protein kinases AKT1/PKB and PLK (Polo-like kinase) have been shown to phosphorylate and regulate the activity of this kinase. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq]

Alternative names:

MYT1; PPP1R126

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

PKMYT1

Isotype:

IgG2a

Immunogen:

Full length human recombinant protein of human PKMYT1 (NP_004194) produced in HEK293T cell.

Clone:

LBI1C3

Conjugation:

Unconjugated

Gene name:

protein kinase, membrane associated tyrosine/threonine 1

Symbol:

PKMYT1

Pathway:

Cell cycle, Oocyte meiosis, Progesterone-mediated oocyte maturation

Function:

Druggable Genome, Protein Kinase

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:500~2000, IF 1:100, FLOW 1:100

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com