Product overview:

Anti-ACO2 (Aconitase 2) mouse monoclonal antibody, clone LBI3G8

Field of research:

Citrate cycle (TCA cycle), Glyoxylate and dicarboxylate metabolism, Metabolic pathways

Summary:

The protein encoded by this gene belongs to the aconitase/IPM isomerase family. It is an enzyme that catalyzes the interconversion of citrate to isocitrate via cis-aconitate in the second step of the TCA cycle. This protein is encoded in the nucleus and functions in the mitochondrion. It was found to be one of the mitochondrial matrix proteins that are preferentially degraded by the serine protease 15(PRSS15), also known as Lon protease, after oxidative modification.

Alternative names:

ACONM; HEL-S-284; ICRD; OCA8; OPA9

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

ACO2

Isotype:

IgG1

Immunogen:

Full length human recombinant protein of human ACO2 (NP_001089) produced in HEK293T cell.

Clone:

LBI3G8

Conjugation:

Unconjugated

Gene name:

aconitase 2

Symbol:

ACO2

Pathway:

Citrate cycle (TCA cycle), Glyoxylate and dicarboxylate metabolism, Metabolic pathways

Function:

Request info at info@sobekbio.com

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

0.9 mg/ml

Form:

PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:2000, IHC 1:50, IF 1:100

Storage buffer:

PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com