Product overview:

Anti-HSPA1A (Hsp70) mouse monoclonal antibody, clone LBI3G9

Field of research:

Antigen processing and presentation, Endocytosis, MAPK signaling pathway, Prion diseases, Spliceosome

Summary:

This intronless gene encodes a 70kDa heat shock protein which is a member of the heat shock protein 70 family. In conjuction with other heat shock proteins, this protein stabilizes existing proteins against aggregation and mediates the folding of newly translated proteins in the cytosol and in organelles. It is also involved in the ubiquitin-proteasome pathway through interaction with the AU-rich element RNA-binding protein 1. The gene is located in the major histocompatibility complex class III region, in a cluster with two closely related genes which encode similar proteins.

Alternative names:

HEL-S-103; HSP70-1; HSP70-1A; HSP70.1; HSP70I; HSP72; HSPA1

Species reactivity:

Human, Monkey, Mouse, Rat, Dog

Host:

Mouse

Target:

HSPA1A

Isotype:

IgG1

Immunogen:

Full length human recombinant protein of human HSPA1A (NP_005336) produced in HEK293T cell.

Clone:

LBI3G9

Conjugation:

Unconjugated

Gene name:

heat shock protein family A (Hsp70) member 1A

Symbol:

HSPA1A

Pathway:

Antigen processing and presentation, Endocytosis, MAPK signaling pathway, Prion diseases, Spliceosome

Function:

Request info at info@sobekbio.com

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:2000, IHC 1:50, IF 1:100

Storage buffer:

PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com