Product overview:

Anti-FKBP5 (FKBP51) mouse monoclonal antibody, clone LBI3E9

Field of research:

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Summary:

The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin. It is thought to mediate calcineurin inhibition.It also interacts functionally with mature hetero-oligomeric progesterone receptor complexes along with the 90 kDa heat shock protein and P23 protein. This gene has been found to have multiple polyadenylation sites. Alternative splicing results in multiple transcript variants.

Alternative names:

AIG6; FKBP51; FKBP54; P54; PPIase; Ptg-10

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

FKBP5

Isotype:

IgG1

Immunogen:

Full-length protein expressed in 293T cell transfected with human FKBP5 expression vector

Clone:

LBI3E9

Conjugation:

Unconjugated

Gene name:

FKBP prolyl isomerase 5

Symbol:

FKBP5

Pathway:

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Function:

Druggable Genome

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:2000, IHC 1:50, IF 1:100

Storage buffer:

PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

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Orders:

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