Product overview:

Anti-AURKC mouse monoclonal antibody, clone LBI2B7

Field of research:

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Summary:

This gene encodes a member of the Aurora subfamily of serine/threonine protein kinases. The encoded protein is a chromosomal passenger protein that forms complexes with Aurora-B and inner centromere proteins and may play a role in organizing microtubules in relation to centrosome/spindle function during mitosis. This gene is overexpressed in several cancer cell lines, suggesting an involvement in oncogenic signal transduction. Alternative splicing results in multiple transcript variants.

Alternative names:

AIE2; AIK3; ARK3; AurC; aurora-C; HEL-S-90; SPGF5; STK13

Species reactivity:

Human

Host:

Mouse

Target:

AURKC

Isotype:

IgG1

Immunogen:

Full-length protein expressed in 293T cell transfected with human AURKC expression vector

Clone:

LBI2B7

Conjugation:

Unconjugated

Gene name:

aurora kinase C

Symbol:

AURKC

Pathway:

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Function:

Druggable Genome, Protein Kinase

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

0.74 mg/ml

Form:

PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB: 1:200 - 1:1000

Storage buffer:

PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

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Orders:

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