Product overview:

Anti-KDM4C mouse monoclonal antibody, clone LBI5B9

Field of research:

Request info at info@sobekbio.com

Summary:

This gene is a member of the Jumonji domain 2 (JMJD2) family and encodes a protein with one JmjC domain, one JmjN domain, two PHD-type zinc fingers, and two Tudor domains. This nuclear protein functions as a trimethylation-specific demethylase, converting specific trimethylated histone residues to the dimethylated form. Chromosomal aberrations and increased transcriptional expression of this gene are associated with esophageal squamous cell carcinoma. Alternative splicing results in multiple transcript variants.

Alternative names:

GASC1; JHDM3C; JMJD2C; TDRD14C

Species reactivity:

Human, Rat

Host:

Mouse

Target:

KDM4C

Isotype:

IgG1

Immunogen:

Full-length protein expressed in 293T cell transfected with human KDM4C expression vector

Clone:

LBI5B9

Conjugation:

Unconjugated

Gene name:

lysine demethylase 4C

Symbol:

KDM4C

Pathway:

Request info at info@sobekbio.com

Function:

Druggable Genome, Transcription Factors

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:2000, IHC 1:50, IF 1:100

Storage buffer:

PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com