Product overview:

Anti-SLC18A2 (VMAT2) mouse monoclonal antibody, clone LBI9E11

Field of research:

Parkinson's disease

Summary:

The vesicular monoamine transporter acts to accumulate cytosolic monoamines into synaptic vesicles, using the proton gradient maintained across the synaptic vesicular membrane. Its proper function is essential to the correct activity of the monoaminergic systems that have been implicated in several human neuropsychiatric disorders. The transporter is a site of action of important drugs,including reserpine and tetrabenazine.

Alternative names:

SVAT; SVMT; VAT2; VMAT2

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

SLC18A2

Isotype:

IgG1

Immunogen:

Full-length protein expressed in 293T cell transfected with human SLC18A2 expression vector .

Clone:

LBI9E11

Conjugation:

Unconjugated

Gene name:

solute carrier family 18 member A2

Symbol:

SLC18A2

Pathway:

Parkinson's disease

Function:

Transmembrane

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:2000, IHC 1:50, IF 1:100, FLOW 1:100

Storage buffer:

PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com