Product overview:

Anti-STK39 mouse monoclonal antibody, clone LBI2E10

Field of research:

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Summary:

This gene encodes a serine/threonine kinase that is thought to function in the cellular stress response pathway. The kinase is activated in response to hypotonic stress, leading to phosphorylation of several cation-chloride-coupled cotransporters. The catalytically active kinase specifically activates the p38 MAP kinase pathway, and its interaction with p38 decreases upon cellular stress, suggesting that this kinase may serve as an intermediate in the response to cellular stress.

Alternative names:

DCHT; PASK; SPAK

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

STK39

Isotype:

IgG1

Immunogen:

Full-length protein expressed in 293T cell transfected with human STK39 expression vector

Clone:

LBI2E10

Conjugation:

Unconjugated

Gene name:

serine/threonine kinase 39

Symbol:

STK39

Pathway:

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Function:

Druggable Genome, Protein Kinase

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:2000 IHC 1:50

Storage buffer:

PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

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Orders:

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