Product overview:

SOD1 (Superoxide Dismutase 1) mouse monoclonal antibody, clone LBI8B10

Field of research:

Amyotrophic lateral sclerosis (ALS), Huntington's disease, Prion diseases

Summary:

The protein encoded by this gene binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis. Rare transcript variants have been reported for this gene. [provided by RefSeq]

Alternative names:

ALS; ALS1; HEL-S-44; homodimer; hSod1; IPOA; SOD

Species reactivity:

Human

Host:

Mouse

Target:

SOD1

Isotype:

IgG2b

Immunogen:

Full length human recombinant protein of human SOD1 (NP_000445) produced in HEK293T cell.

Clone:

LBI8B10

Conjugation:

Unconjugated

Gene name:

superoxide dismutase 1

Symbol:

SOD1

Pathway:

Amyotrophic lateral sclerosis (ALS), Huntington's disease, Prion diseases

Function:

Druggable Genome

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:1000~2000, IHC 1:50, FLOW 1:100

Storage buffer:

PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com