Product overview:

Mouse monoclonal anti-HSP90AB1(HSP90) antibody, clone 4C10, Load, clone LBI4C10

Field of research:

Antigen processing and presentation, NOD-like receptor signaling pathway, Pathways in cancer, Progesterone-mediated oocyte maturation, Prostate cancer

Summary:

HSP90 proteins are highly conserved molecular chaperones that have key roles in signal transduction, protein folding, protein degradation, and morphologic evolution. HSP90 proteins normally associate with other cochaperones and play important roles in folding newly synthesized proteins or stabilizing and refolding denatured proteins after stress. There are 2 major cytosolic HSP90 proteins, HSP90AA1 (MIM 140571), an inducible form, and HSP90AB1, a constitutive form. Other HSP90 proteins are found in endoplasmic reticulum (HSP90B1; MIM 191175) and mitochondria (TRAP1; MIM 606219)

Alternative names:

D6S182; HSP84; HSP90B; HSPC2; HSPCB

Species reactivity:

Human, Monkey, Mouse, Rat, Dog

Host:

Mouse

Target:

HSP90AB1

Isotype:

IgG2b

Immunogen:

Full-length protein expressed in 293T cell transfected with human HSP90AB1 expression vector

Clone:

LBI4C10

Conjugation:

Unconjugated

Gene name:

heat shock protein 90 alpha family class B member 1

Symbol:

HSP90AB1

Pathway:

Antigen processing and presentation, NOD-like receptor signaling pathway, Pathways in cancer, Progesterone-mediated oocyte maturation, Prostate cancer

Function:

Druggable Genome, Stem cell - Pluripotency

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:2000

Storage buffer:

PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

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