Product overview:

Anti-RAD9A (RAD9) mouse monoclonal antibody, clone LBI7B11

Field of research:

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Summary:

This gene product is highly similar to Schizosaccharomyces pombe rad9, a cell cycle checkpoint protein required for cell cycle arrest and DNA damage repair in response to DNA damage. This protein is found to possess 3' to 5' exonuclease activity, which may contribute to its role in sensing and repairing DNA damage. It forms a checkpoint protein complex with RAD1 and HUS1. This complex is recruited by checkpoint protein RAD17 to the sites of DNA damage, which is thought to be important for triggering the checkpoint-signaling cascade. Use of alternative polyA sites has been noted for this gene.

Alternative names:

RAD9

Species reactivity:

Human

Host:

Mouse

Target:

RAD9A

Isotype:

IgG2a

Immunogen:

Full-length protein expressed in 293T cell transfected with human RAD9A expression vector

Clone:

LBI7B11

Conjugation:

Unconjugated

Gene name:

RAD9 checkpoint clamp component A

Symbol:

RAD9A

Pathway:

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Function:

Druggable Genome, Stem cell - Pluripotency

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

2 mg/ml

Form:

PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:2000 IHC 1:50

Storage buffer:

PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

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