Product overview:

Anti-NTRK2 (TrkB ) mouse monoclonal antibody, clone LBI2E1

Field of research:

MAPK signaling pathway, Neurotrophin signaling pathway

Summary:

This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation. Mutations in this gene have been associated with obesity and mood disorders. Alternate transcriptional splice variants encoding different isoforms have been found for this gene

Alternative names:

GP145-TrkB; trk-B; TRKB

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

NTRK2

Isotype:

IgG1

Immunogen:

Full-length protein expressed in 293T cell transfected with human NTRK2 expression vector

Clone:

LBI2E1

Conjugation:

Unconjugated

Gene name:

neurotrophic receptor tyrosine kinase 2

Symbol:

NTRK2

Pathway:

MAPK signaling pathway, Neurotrophin signaling pathway

Function:

Druggable Genome, Protein Kinase, Transmembrane

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1.17 mg/ml

Form:

PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:1000, IHC 1:150, IF 1:100

Storage buffer:

PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com