Product overview:

Anti-PLK1 mouse monoclonal antibody, clone LBI3F12

Field of research:

Cell cycle, Oocyte meiosis, Progesterone-mediated oocyte maturation

Summary:

Serine/threonine-protein kinase that performs several important functions throughout M phase of the cell cycle, including the regulation of centrosome maturation and spindle assembly, the removal of cohesins from chromosome arms, the inactivation of APC/C inhibitors, and the regulation of mitotic exit and cytokinesis

Alternative names:

PLK; STPK13

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

PLK1

Isotype:

IgG1

Immunogen:

Full-length protein expressed in 293T cell transfected with human PLK1 expression vector

Clone:

LBI3F12

Conjugation:

Unconjugated

Gene name:

polo like kinase 1

Symbol:

PLK1

Pathway:

Cell cycle, Oocyte meiosis, Progesterone-mediated oocyte maturation

Function:

Druggable Genome, Protein Kinase

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1.01 mg/ml

Form:

PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:2000, IHC 1:150, FLOW 1:100, IP 2ug/500ul

Storage buffer:

PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com