Product overview:

AK1 (Adenylate Kinase 1) mouse monoclonal antibody, clone LBI19D1

Field of research:

Metabolic pathways, Purine metabolism

Summary:

Adenylate kinase is an enzyme involved in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate group among adinine nucleotides. Three isozymes of adenylate kinase have been identified in vertebrates, adenylate isozyme 1 (AK1), 2 (AK2) and 3 (AK3). AK1 is found in the cytosol of skeletal muscle, brain and erythrocytes, whereas AK2 and AK3 are found in the mitochondria of other tissues including liver and heart. AK1 was identified because of its association with a rare genetic disorder causing nonspherocytic hemolytic anemia where a mutation in the AK1 gene was found to reduce the catalytic activity of the enzyme.

Alternative names:

HTL-S-58j

Species reactivity:

Human, Monkey, Mouse, Rat

Host:

Mouse

Target:

AK1

Isotype:

IgG2b

Immunogen:

Full length human recombinant protein of human AK1 (NP_000467) produced in HEK293T cell.

Clone:

LBI19D1

Conjugation:

Unconjugated

Gene name:

adenylate kinase 1

Symbol:

AK1

Pathway:

Metabolic pathways, Purine metabolism

Function:

Druggable Genome

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1.2 mg/ml

Form:

PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:1000~2000, IF 1:50, FLOW 1:100

Storage buffer:

PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com