Product overview:

ID2 mouse monoclonal antibody, clone LBI9A8

Field of research:

TGF-beta signaling pathway

Summary:

The protein encoded by this gene belongs to the inhibitor of DNA binding (ID) family, members of which are transcriptional regulators that contain a helix-loop-helix (HLH) domain but not a basic domain. Members of the ID family inhibit the functions of basic helix-loop-helix transcription factors in a dominant-negative manner by suppressing their heterodimerization partners through the HLH domains. This protein may play a role in negatively regulating cell differentiation. A pseudogene has been identified for this gene.

Alternative names:

bHLHb26; GIG8; ID2A; ID2H

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

ID2

Isotype:

IgG1

Immunogen:

Full length human recombinant protein of human ID2 (NP_002157) produced in E.coli.

Clone:

LBI9A8

Conjugation:

Unconjugated

Gene name:

inhibitor of DNA binding 2

Symbol:

ID2

Pathway:

TGF-beta signaling pathway

Function:

ES Cell Differentiation/IPS, Stem cell relevant signaling - TGFb/BMP signaling pathway, Transcription Factors

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:500, IHC 1:50, IF 1:100

Storage buffer:

PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com