Product overview:

Anti-OSM (Oncostatin M) mouse monoclonal antibody, clone LBI2B6

Field of research:

Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway

Summary:

Oncostatin M is a member of a cytokine family that includes leukemia-inhibitory factor, granulocyte colony-stimulating factor, and interleukin 6. This gene encodes a growth regulator which inhibits the proliferation of a number of tumor cell lines. It regulates cytokine production, including IL-6, G-CSF and GM-CSF from endothelial cells

Alternative names:

MGC20461

Species reactivity:

Human

Host:

Mouse

Target:

OSM

Isotype:

IgG1

Immunogen:

Recombinant protein expressed in E.coli corresponding to amino acids 25-252 of human OSM

Clone:

LBI2B6

Conjugation:

Unconjugated

Gene name:

oncostatin M

Symbol:

OSM

Pathway:

Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway

Function:

Druggable Genome, ES Cell Differentiation/IPS, Secreted Protein, Stem cell relevant signaling - DSL/Notch pathway, Stem cell relevant signaling - JAK/STAT signaling pathway

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:1000, IHC 1:50

Storage buffer:

PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com