Product overview:

EpCAM mouse monoclonal antibody, clone LBI2C8

Field of research:

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Summary:

EpCAM is a carcinoma-associated antigen and is a member of a family that includes at least two type I membrane proteins. This antigen is expressed on most normal epithelial cells and gastrointestinal carcinomas and functions as a homotypic calcium-independent cell adhesion molecule. The antigen is being used as a target for immunotherapy treatment of human carcinomas.

Alternative names:

DIAR5; EGP-2; EGP40; EGP314; ESA; HNPCC8; KS1/4; KSA; M4S1; MIC18; MK-1; TACSTD1; TROP1

Species reactivity:

Human

Host:

Mouse

Target:

EPCAM

Isotype:

IgM

Immunogen:

Human recombinant protein fragment corresponding to amino acids 24-265 of human EpCAM (NP_002345) produced in E.coli.

Clone:

LBI2C8

Conjugation:

Unconjugated

Gene name:

epithelial cell adhesion molecule

Symbol:

EPCAM

Pathway:

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Function:

ES Cell Differentiation/IPS, Transmembrane

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:200~500, IHC 1:50

Storage buffer:

PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

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Orders:

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