Product overview:

Anti-FOXA2 mouse monoclonal antibody, clone LBI3C10

Field of research:

Maturity onset diabetes of the young

Summary:

FOXA2 is a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific genes such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver. This gene has been linked to sporadic cases of maturity-onset diabetes of the young. Transcript variants encoding different isoforms have been identified for this gene

Alternative names:

HNF3B; TCF3B

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

FOXA2

Isotype:

IgG1

Immunogen:

Recombinant protein expressed in E.coli corresponding to amino acids 300-458 of human FOXA2

Clone:

LBI3C10

Conjugation:

Unconjugated

Gene name:

forkhead box A2

Symbol:

FOXA2

Pathway:

Maturity onset diabetes of the young

Function:

Embryonic stem cells, ES Cell Differentiation/IPS, Induced pluripotent stem cells, Transcription Factors

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB: 1:1000; IHC: 1:50; IF: 1:50-1:100; Flow 1:1,000

Storage buffer:

PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com