Product overview:

SERPINA1 mouse monoclonal antibody, clone LBI3C5

Field of research:

Complement and coagulation cascades

Summary:

A1AT is secreted and is a serine protease inhibitor whose targets include elastase, plasmin, thrombin, trypsin, chymotrypsin, and plasminogen activator. Defects in A1AT gene can cause emphysema or liver disease. Several transcript variants encoding the same protein have been found for this gene.

Alternative names:

A1A; A1AT; AAT; alpha1AT; PI; PI1; PRO2275

Species reactivity:

Human

Host:

Mouse

Target:

SERPINA1

Isotype:

IgG2b

Immunogen:

Human recombinant protein fragment corresponding to amino acids 26-418 of human A1AT (NP_000286) produced in E.coli.

Clone:

LBI3C5

Conjugation:

Unconjugated

Gene name:

serpin family A member 1

Symbol:

SERPINA1

Pathway:

Complement and coagulation cascades

Function:

Druggable Genome, ES Cell Differentiation/IPS, Secreted Protein

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:1000~2000

Storage buffer:

PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com