Product overview:

NT4 (Neurotrophin 4) mouse monoclonal antibody, clone LBI2E8

Field of research:

MAPK signaling pathway, Neurotrophin signaling pathway

Summary:

NT4 is a member of a family of neurotrophic factors, neurotrophins, that control survival and differentiation of mammalian neurons. The expression of NT4 is ubiquitous and less influenced by environmental signals. While knock-outs of other neurotrophins including nerve growth factor, brain-derived neurotrophic factor, and neurotrophin 3 prove lethal during early postnatal development, NT4-deficient mice only show minor cellular deficits and develop normally to adulthood.

Alternative names:

5; GLC1O; GLC10; NT-4; NT-5; NT4; NT5; NTF5

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

NTF4

Isotype:

IgG1

Immunogen:

Human recombinant protein fragment corresponding to amino acids 81-210 human NT4 (NP_006170) produced in E.coli.

Clone:

LBI2E8

Conjugation:

Unconjugated

Gene name:

neurotrophin 4

Symbol:

NTF4

Pathway:

MAPK signaling pathway, Neurotrophin signaling pathway

Function:

Druggable Genome, Secreted Protein

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:5000, IHC 1:50, IF 1:50

Storage buffer:

PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com