Product overview:

Anti-NT3 (Neurotrophin 3) mouse monoclonal antibody, clone LBI5A2

Field of research:

MAPK signaling pathway, Neurotrophin signaling pathway

Summary:

NT3 is a member of the neurotrophin family, that controls survival and differentiation of mammalian neurons. It is closely related to both nerve growth factor and brain-derived neurotrophic factor. It may be involved in the maintenance of the adult nervous system, and may affect development of neurons in the embryo when it is expressed in human placenta. NT3-deficient mice generated by gene targeting display severe movement defects of the limbs. The mature peptide of this protein is identical in all mammals examined including human, pig, rat and mouse

Alternative names:

HDNF; NGF-2; NGF2; NT-3; NT3

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

NTF3

Isotype:

IgG1

Immunogen:

Recombinant protein expressed in E.coli corresponding to amino acids 139-257 of human NT3

Clone:

LBI5A2

Conjugation:

Unconjugated

Gene name:

neurotrophin 3

Symbol:

NTF3

Pathway:

MAPK signaling pathway, Neurotrophin signaling pathway

Function:

Druggable Genome, Secreted Protein

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1.5 mg/ml

Form:

PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB: 1:5000, IHC 1:50, IF (1:100)

Storage buffer:

PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

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