Product overview:

ESRRA mouse monoclonal antibody, clone LBI3G10

Field of research:

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Summary:

The protein encoded by this gene is a nuclear receptor that is closely related to the estrogen receptor. This protein acts as a site-specific transcription regulator and has been also shown to interact with estrogen and the transcripton factor TFIIB by direct protein-protein contact. The binding and regulatory activities of this protein have been demonstrated in the regulation of a variety of genes including lactoferrin, osteopontin, medium-chain acyl coenzyme A dehydrogenase (MCAD) and thyroid hormone receptor genes. A processed pseudogene of ESRRA is located on chromosome 13q12.1. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2013]

Alternative names:

ERR1; ERRa; ERRalpha; ESRL1; NR3B1

Species reactivity:

Human

Host:

Mouse

Target:

ESRRA

Isotype:

IgG1

Immunogen:

Human recombinant protein fragment corresponding to amino acids 206-417 of human ESRRA (NP_004442) produced in E.coli.

Clone:

LBI3G10

Conjugation:

Unconjugated

Gene name:

estrogen related receptor alpha

Symbol:

ESRRA

Pathway:

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Function:

Druggable Genome, Nuclear Hormone Receptor, Transcription Factors

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:2000

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

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Orders:

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