Product overview:

PMP22 mouse monoclonal antibody,clone LBI5D1

Field of research:

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Summary:

This gene encodes an integral membrane protein that is a major component of myelin in the peripheral nervous system. Studies suggest two alternately used promoters drive tissue-specific expression. Various mutations of this gene are causes of Charcot-Marie-Tooth disease Type IA, Dejerine-Sottas syndrome, and hereditary neuropathy with liability to pressure palsies. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]

Alternative names:

CMT1A; CMT1E; DSS; GAS-3; GAS3; HMSNIA; HNPP; Sp110

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

PMP22

Isotype:

IgG1

Immunogen:

Full length human recombinant protein of human PMP22 (NP_000295) produced in HEK293T cell.

Clone:

LBI5D1

Conjugation:

Unconjugated

Gene name:

peripheral myelin protein 22

Symbol:

PMP22

Pathway:

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Function:

Transmembrane

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:500, IHC 1:2000

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

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Orders:

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