Product overview:

MXD4 mouse monoclonal antibody,clone LBI7F7

Field of research:

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Summary:

This gene is a member of the MAD gene family . The MAD genes encode basic helix-loop-helix-leucine zipper proteins that heterodimerize with MAX protein, forming a transcriptional repression complex. The MAD proteins compete for MAX binding with MYC, which heterodimerizes with MAX forming a transcriptional activation complex. Studies in rodents suggest that the MAD genes are tumor suppressors and contribute to the regulation of cell growth in differentiating tissues. [provided by RefSeq, Jul 2008]

Alternative names:

bHLHc12; MAD4; MST149; MSTP149

Species reactivity:

Human, Mouse

Host:

Mouse

Target:

MXD4

Isotype:

IgG2b

Immunogen:

Full length human recombinant protein of human MXD4(NP_006445) produced in E.coli.

Clone:

LBI7F7

Conjugation:

Unconjugated

Gene name:

MAX dimerization protein 4

Symbol:

MXD4

Pathway:

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Function:

Druggable Genome, Transcription Factors

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:2000, IHC 1:150

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

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Orders:

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